Past Group Leaders
 Ralf Adams
Research Goals
To understand the molecular mechanisms underlying cell-cell communication, adhesion and migration during normal tissue morphogenesis and to gain insight into their potential relevance for cancer and other disease conditions.
Qualifications and Personal History
PhD 1996 Max Planck Institute for Brain Research, Frankfurt
Postdoctoral work at the European Molecular Biology Laboratory in Heidelberg, Germany
Head of Vascular Development Laboratory at the Cancer Research UK London Research Institute from 2000 to 2007
Director of the Tissue Morphogenesis Department at the Max Planck Institute for Molecular Biomedicine from 2008 to present.
Researcher's website: www.mpi-muenster.mpg.de
 John Fox
Research Goals
To carry out research in formal computer science and its applications in biomedicine, focusing on artificial intelligence and cognitive systems, as the basis for developing innovative information technologies to support patient care.
Qualifications and Personal History
PhD 1974 Cambridge University.
Postdoctoral work at Carnegie-Mellon University, Pittsburgh, and at Cornell University, Ithaca, New York.
Head of the Advanced Computation Laboratory at the Cancer Research UK London Research Institute from 1987 to 2007.
Professor of Engineering Science at University of Oxford from 2008 to present.
Researcher's website: www.cossac.org
 Tomas Lindahl
Research Goals
By definition of the mechanisms and efficiencies of DNA repair processes, we aim to clarify cellular resistance to carcinogens, as well as elucidate the acquired drug and radiation resistance that often emerges in cancer patients.
Qualifications and Personal History
MD 1970 Karolinska Institute, Stockholm.
Postdoctoral work at Princeton University and Rockefeller University, USA.
Joined Imperial Cancer Research Fund (now known as Cancer Research UK) in 1981.
Retired from the London Research Institute in 2010.
 Denise Sheer
Research Goals
To study genome biology and cancer genetics. A major aim of our research is to understand the structural and functional organisation of the human genome and the nucleus. While the first level of packaging, the nucleosomal fibre, is well characterised, little is known about higher order chromatin structure or chromosome territories.
Qualifications and Personal History
1980 - DPhil, University of Oxford
1980-1983 - Post-Doctoral Research Fellowship at the Imperial Cancer Research Fund (ICRF)
1983-2006 - Group leader of the Human Cytogenetics Laboratory (ICRF)
from 2006 - Professor of Human Genetics at the Institute of Cell and Molecular Science
Institute website: www.icms.qmul.ac.uk
 Ian Tomlinson
Research Goals
To identify cancer predisposition genes.
To identify genetic changes that predict response to cancer therapy or indicate prognosis.
To work out molecular pathways of tumorigenesis.
To use genetic methods to elucidate the functional effects of mutations in tumour growth.
To set up model systems for the analysis of tumorigenesis.
To produce information that is clinically relevant.
Qualifications and Personal History
PhD 1988 University of Cambridge.
Postdoctoral work at Imperial Cancer Research Fund (ICRF), Institute of Cancer Research (ICR) and Oxford.
Group leader of the Molecular and Population Genetics Laboratory at the London Research Institute from 1998 to 2009.
Group leader of the Molecular and Population Genetics Group at the Nuffield Department of Clinical Medicine, University of Oxford from 2009 to present.
Researcher's website: www.ndm.ox.ac.uk.
 Alain Verreault
Research Goals
Because of the high frequency of S-phase cells in tumours, the enzymes involved in nucleosome assembly represent attractive targets for cancer diagnosis and chemotherapy. We investigate the factors and processes involved in de novo nucleosome assembly during S-phase.
Qualifications and Personal History
1993 - PhD, University of Cambridge
1994-1998 - Postdoctoral Fellow Cold Spring Harbor
1999-2005 - Group Leader of the Chromosome Dynamics Laboratory Imperial Cancer Research Institute
From 2005 - Group leader of Chromosome Biosynthesis Laboratory Institute for Research in Immunology and Cancer, University of Montreal
Researcher website: www.iric.ca/Recherche/Chercheurs/Verreault_A_EN.html
 Fiona Watt
Research Goals
To understand how the proliferation, differentiation and tissue assembly of epidermal stem cells and their progeny are controlled, and how these processes are perturbed in cancer.
Qualifications and Personal History
1979 - DPhil, University of Oxford
Postdoctoral work at MIT, Cambridge, USA.
1987-2006 - Head of Laboratory at Cancer Research UK London Research Institute
From 2006 - Deputy Director of Cancer Research UK Cambridge Research Institute
Researcher website: http://www.bio.cam.ac.uk/~wattlab/index.html
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