Selected Publications
Tapon N, Harvey KF, Bell DW, Wahrer DCR, Schiripo TA, Haber DA and Hariharan IK. Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 2002; 110: 467-478. PubMed
Tapon N, Moberg KH and Hariharan IK. The coupling of cell growth to the cell cycle. Curr. Opin. Cell Biol. 2001; 13: 731-737. PubMed
Tapon N, Ito N, Dickson BJ, Treisman JE and Hariharan IK The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 2001; 105: 345-355. PubMed
Primary Research Publications
2010
Genevet A, Wehr MC, Brain R, Thompson BJ, Tapon N. Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network. Dev Cell 2010; 18 (2):300-308. UKPubMed (open access); PubMed; DOI: 10.1016/j.devcel.2009.12.011.
Cully M, Genevet A, Warne P, Treins C, Liu T, Bastien J, Baum B, Tapon N, Leevers SJ, Downward J. A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1. Mol Cell Biol 2010; 30 (2):481-495. UKPubMed (open access); PubMed; DOI: 10.1128/MCB.00688-09.
2009
Langton PF, Colombani J, Chan EHY, Wepf A, Gstaiger M, Tapon N. The dASPP-dRASSF8 Complex Regulates Cell-Cell Adhesion during Drosophila Retinal Morphogenesis. Curr Biol 2009; 19 (23):1969-1978. PubMed; DOI: 10.1016/j.cub.2009.10.027.
Genevet A, Polesello C, Blight K, Robertson F, Collinson LM, Pichaud F, Tapon N. The Hippo pathway regulates apical-domain size independently of its growth-control function. J Cell Sci 2009; 122 (14):2360-2370. UKPubMed (open access); PubMed; DOI: 10.1242/jcs.041806.
Tain LS, Chowdhury RB, Tao RN, Plun-Favreau H, Moisoi N, Martins LM, Downward J, Whitworth AJ, Tapon N. Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin. Cell Death Differ 2009; 16 (8):1118-1125. UKPubMed (open access); PubMed; DOI: 10.1038/cdd.2009.23.
2008
Tapon N, Ziebold U. Invasion and metastasis: stem cells, screens and survival Conference on Invasion and Metastasis. EMBO Rep 2008; 9 (11):1078-1083. UKPubMed (open access); PubMed; DOI: 10.1038/embor.2008.187.
Andersen DS, Tapon N. Drosophila MFAP1 Is Required for Pre-mRNA Processing and G(2)/M Progression. J Biol Chem 2008; 283 (45):31256-31267. UKPubMed (open access); PubMed; DOI: 10.1074/jbc.M803512200.
Dobbelaere J, Josue F, Suijkerbuijk S, Baum B, Tapon N, Raff J. A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol 2008; 6 (9):1975-1990. PubMed.
2007
Langton PF, Colombani J, Aerne BL, Tapon N. Drosophila ASPP regulates C-terminal Src kinase activity. Dev Cell 2007; 13 (6):773-782.
Polesello C, Tapon N. Salvador-Warts-Hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol 2007; 17 (21):1864-1870.
Tseng ASK, Tapon N, Kanda H, Cigizoglu S, Edelmann L, Pellock B, White K, Hariharan IK. Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/Ras signaling pathway. Curr Biol 2007; 17 (8):728-733.
Harvey K, Tapon N. The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer 2007; 7 (3):182-191.
2006
Polesello C, Huelsmann S, Brown NH, Tapon N. The Drosophila RASSF homolog antagonizes the Hippo pathway. Curr Biol 2006; 16 (24):2459-2465. DOI: 10.1016/j.cub.2006.10.060.
Silva E, Tsatskis Y, Gardano L, Tapon N, McNeill H. The tumor-suppressor gene fat controls tissue growth upstream of Expanded in the Hippo signaling pathway. Curr Biol 2006; 16 (21):2081-2089.
Colombani J, Polesello C, Josue F, Tapon N. Dmp53 activates the hippo pathway to promote cell death in response to DNA damage. Curr Biol 2006; 16 (14):1453-1458.
2003
Tapon N. Modeling transformation and metastasis in Drosophila. Cancer Cell 2003; 4 (5):333-335.
|
