LRI Research Portfolio

Research at the Cancer Research UK London Research Institute (LRI) aims to understand two phenomena central to our understanding of cancer development and spread, which are intimately connected through their interactions with the cell cycle. First, the nature and role of the signalling process which control both the intrinsic properties of cancer cells, and their interactions with their host; and second, how the integrity of the genome is maintained in the face of multiple environmental and endogenous insults.

The LRI's research portfolio focuses around two themes - signal transduction (biology of tissues and organs, and molecular cell biology) and genome integrity (cell cycle and chromosomes, and DNA repair).

Within the Institute, an interactive, inter-disciplinary faculty is fostered through common research tools, approaches and model organisms in addition to the major themes. Research 'interest groups', rather than formal divisions, promote an informal and dynamic network of scientific discourse between LRI scientists.

There are currently 46 research groups within the LRI - 33 at Lincoln's Inn Fields and 12 at Clare Hall. See the list below for links to the researcher's homepage within the Cancer Research UK Research Directory. Summaries of the Group Leaders' research areas (organised by research themes) are available to download as PDFs from the Related Documents list on the right.